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Although there are no built-in cheats for Slay the Spire, players can download a trainer for the game that enables you to put the cheats into the game yourself. The trainer will allow you to use cheats such as the following.
Once you have downloaded and installed the trainer.
In the main menu, press F1 and listen closely for “Trainer Activated”.
This opens up the ability to press the desired hotkey.
Press Numpad 1 to set your Health.
Press Numpad 2 to set your gold amount.
Press Numpad 3 to set the number of cards you can play.
Press Numpad 4 to Get Unlimited Energy.
With regards to Health and Gold, the game has a tendency to notice when you have more than the average amount and will adjust, so make sure to set just enough to get you through the battle comfortably. If you would like to mute the hotkeys while playing so that you do not accidentally press them, you can press CTRL - H to mute and unmute the hotkeys.
WIthin Slay the Spire, there are many relics to collect, some of these relics have some interesting power within them. If you were to pay close attention, the Centennial Puzzle is a reference to the Millenium Puzzle from the popular cartoon, Yu-Gi-Oh.
Each of the three players have their own set of cards to unlock. The way in which you unlock these cards is nothing easier than to earn points on each hero. To earn the points, simply play through games, at the end of each game, you will be awarded points based on the number of enemies defeated, bosses tainted, etc.
Relics are collectible content that gives a boost to certain stats until the end of the run. So finding Relics are an important step toward becoming the best. Obtaining these Relics are just like unlocking the cards, throughout the games, there is a chance that the Relics will drop for you. As long as you have not collected a Relic, there is a chance that it will drop for you during a game. Some Relics however are part of unlockable content ( marked with a lock and chains over them), these relics will not drop for you as long as they are still locked.
Not really thought of like a glitch or bug, but something to exploit, the method dubbed “Savescumming” can save you tons of hours of frustration. The method involves saving mid-game, then quitting and coming back into the game. The game you were playing will play out in exactly the same way if you were to use the exact same moves. So you can use this to your advantage and play your game out with different decisions and hopefully scrape the win for yourself.
The most common question when starting a game such as Slay the Spire is generally always, “what is the best class?” or “What are the best cards?”. The straight answer is never really straight anyway, it all depends on the situation. Knowing about the type of opponents and the strength and weaknesses of your class will mean the difference between wins and losses.
The best way in which to progress with the least amount of difficulty is by choosing the correct path. Slay the Spire has elements of a dungeon crawler, which just means that the player ends up at crossroads and has to choose which way to progress. In Slay the Spire, the best choice of the road is one in which you would start by facing around 3 normal bosses. From then on, make sure that you have a rest before the Elemental Bosses, if not to heal, then upgrade cards to make the battle a little bit easier.
One mistake many people make when playing card-based games is to think that if you have the deck that is the most complicated with every card buffing another that you will win every battle. The best solution, however, is to simplify the deck that you choose to take. Having multiple cards that work off each other is great if you have a few of each, but don’t stack your whole deck to be dependent on a few cards. Now that is asking for trouble. Make use of the card removal tool at every rest stop. You can use this to remove any troublesome curses and other cards from your deck.
Mistakes that players can make when playing games, is to ignore the aspects that they do not like and hate playing. This is not a very great strategy as you will have no idea how to play against that type of enemy. The best strategy that you can adopt is one of practicing every element of the game, especially the element that you do not like playing. Learning these elements will help you beat the ones that you do not like easier and have less frustration while playing against them.
Many players tend to avoid the elite fights when choosing a path, I mean, why fight the harder fights? While this thought does hold true in some aspects, it is not the best decision in others. Elite fights are the best source of Relics and will give you the best learning curve while teaching you the best loot. In addition, Elites are more predictable, so you might find more success in elite fights over regular fights.