Cole McGrath's Electronics
During the boss battle with Eugene there should be a set of two red doors in his 'lair'. On these doors it is written Cole McG's Electronics with a small blue lightning bolt above it. This is a reference to the first two infamous game's protagonist Cole McGrath who had the ability to use electricity.
Prototype 2 Alex Mercer Reference
At first when you get to the bridge the the DUP destroyed in therror mini cutscene you will see road sign that says ' Mercer St'.
Mega Vent Glitch
This is a glitch you can do with smoke power and a vent. This glitch will allow you to gain lots of height, sometimes enough to shoot you into a kill plain very high up.
Find a vent and enter it. While you are in the vent, start rotating the left stick in circles quickly.
When you exit the vent, wait a split second and press the circle button, and then wait another split second before hitting the square button. You should gain enough height to go far above the space needle and D.U.P. Tower.
If you can't get it, keep trying and try messing with the timings.
Note: Sometimes spamming circle in the vent will help with your timing.
Other note: This glitch was discovered by a YouTuber and Twitch streamer by the name of Macasadia
By: The anonymous dude
You can use your Smoke powers to deal ranged damage from rooftops. If you also use it to escape enemies via vents, you will almost never be in danger.
Even when you have cleared enemies from a location, more will spawn during DUP raids. The raid location will be marked with a red circle on your map.
Hat Trick Trophy Easy
To easily get the "Hat Trick" trophy, find either a lone enemy or take out all but one enemy in a group. Shoot the single enemy one time with each power before killing him.
Karmic Streak Attacks
Your karmic streak attacks can help you out of bad situations. They're especially effective when you're fighting the dangerous enemies at Mobile Command Centers. Build them up (by killing enemies, executing enemies who have surrendered, and killing civilians for Evil Karma, and by non-lethally incapacitating enemies, accepting surrenders, and saving civilians for Good Karma) and use them when you're in trouble.
If you're having trouble, take a break from the main story to do some more side missions, especially the Stencil Art ones.
Keep it Up Trophy Easy
To easily get the "Keep It Up" trophy, you must have the Video Power and the Airwave skill. Go to the northeast and find the highest skyscraper in the Belltown district. At the top, enter a satellite dish to be launched into the air. Then, hold the X button to glide and use the Airwave ability to remain in the air long enough for the trophy.
Keep an Eye Out
- If you use the rooftops to travel around the city, you will have fewer enemy encounters. To clear out the enemies in a given distract, you must destroy the Core Relay and reduce the D.U.P.'s level of control to 30% or lower. You can then fight them once and for all in a District Showdown.
- Keep an eye on the map to spot D.U.P. cameras. Destroy them before they catch you and alert the D.U.P.
- If you're fighting enemies that are on a rooftop, you can hang from the edge to use the wall itself as cover, and shoot them. This is a useful tactic for the He Who Dwells boss battle.
Total CARnage Trophy Easy
To easily get the "Total CARnage" trophy, use the Smoke Power's fully upgraded Cinder Missile ability, which will allow you to use 5 missiles. Go to the street and wait for five cars to come along, and then shoot each one with a missile. It is also possible to get this trophy in a parking lot.
You can get Blast Shards from Core Relay stations, Tracker Drones, and checkpoints. Whenever you destroy a Core Relay, you'll be able to see the locations of the Blast Shards in that district. Get as many as you can to upgrade your powers. Your first priority should be to upgrade the abilities you will need the most. Light Speed Run and Cinder Missile are two good choices. As you progress in the game, you might consider saving some of your Blast Shards in case you encounter the need for a specific upgraded power.
Double Smoke Stack Attack Trophy Easy
To easily get the "Double Smoke Stack Attack" trophy, go to Uptown and head to the DUP command center on the left side of the map. Use your Vent Dash power to enter a red vent on the street level. Next, use Double Dash and Glide to make your way to a second vent. When it launches you into the air, use Comet Drop on the DUP mobile command platform.
Karma System and Powers
Due to the way the karma system affects your powers, you shouldn't switch between the two or try to balance them. If you're going to follow the Good path, try to always perform Good actions. If you're going to follow the Evil path, try to always perform Evil actions.
- Take the time to learn how your powers work, so you can choose the best one for any situation. You should also practice your melee and close-range fighting skills to prepare yourself for later boss battles where you can't hide or fight from the rooftops.
- Smoke power is good for close-range attacks, but it is the slowest transportation power.
- Neon power is good for transportation and long-range attacks, but not for close-range.
Cough Drop Trophy Easy
To easily get the "Cough Drop" trophy, find a random spawn of drug dealers, marked with a blue syringe on the map. They will always spawn, regardless of your karma and progress in the story. Throw a Sulfur Bomb, let it detonate, and then jump into the air to use Comet Drop to hit three at once. To make it even easier, get the Corrosive Fumes and Giant Sulfur Bomb upgrades first.
Certain objects, including Signal Jammers and Mobile Command Center helicopters, will be permanently gone as soon as you destroy them. If you're having trouble fighting through the enemies to reach one, you can rush in, destroy it, and die. When you respawn, it will still be destroyed.
Early on, you should decide if you want to take the Good Karma path or the Evil Karma path. For Evil Karma, you will need to be quick and destructive, and for Good Karma, you will need to be precise and merciful.